2024

Mejaes, J. I., Saenz, J., O’Brien, C., Pizzano, C. M., Pan, P. Y., & Barker, D. J. (2024). Haploinsufficiency of the Parkinson’s disease gene synaptojanin1 is associated with abnormal responses to psychomotor stimulants and mesolimbic dopamine signaling. Frontiers in Behavioral Neuroscience, 18, 1359225.

Millard, S. J., Hoang, I. B., Greer, Z., O’Connor, S. L., Wassum, K. M., James, M. H., Barker, D.J & Sharpe, M. J. (2024). Cognitive representations of intracranial self-stimulation of midbrain dopamine neurons depend on stimulation frequency. Nat Neurosci (2024). https://doi.org/10.1038/s41593-024-01643-1 .

2023

Barker, D. J., Zhang, S., Wang, H., Estrin, D. J., Miranda-Barrientos, J., Liu, B., Kulkarni RJ, deDeus JL, & Morales, M. (2023). Lateral preoptic area glutamate neurons relay nociceptive information to the ventral tegmental area. Cell Reports, 42(9).

Crawley AK, Sharma A, Coffey KR, West MO, Barker DJ. (2023). Nucleus Accumbens Shell Neurons’ Early Sensitivity to Cocaine is Associated with Future Increases in Drug Intake. Addiction Neuroscience, Addiction Neuroscience, 8(2023), 100107

Saenz J, Yao O, Aggarwal M, Zhou X, Barker DJ, Dicicco-Bloom E, Pan P. (2023) A novel pH-sensitive reporter reveals the cocaine-regulated trafficking of dopamine transporters in neuronal processes, iScience, 26(1), 105782.

Bryant, S, Balouek-Thomert, J, Geiger, LT, Barker, DJ, Peña, CJ (2023) Neuropathic pain as a trigger for histone modifications in limbic circuitry. Genes, Brain, and Behavior, 2022; 1-8. doi: 10.1111/gbb.12830.

2022

Mejaes J., Desai, D., Siciliano, C.A., Barker D.J. (2022). Practical opinions for new fiber photometry users to obtain rigorous recordings and avoid pitfalls. Pharmacology, Biochemistry, and Behavior, 221, 173488. https://doi.org/10.1016/j.pbb.2022.173488.

Waung, M. W., Maanum, K. A., Cirino, T. J., Driscoll, J. R., O’Brien, C., Bryant, S., Mansourian, K.A., Morales, M., Barker, D.J., & Margolis, E. B. (2022). A diencephalic circuit in rats for opioid analgesia but not positive reinforcement. Nature Communications, 13(1), 1-13.

O’Brien C, Vemireddy R, Mohammed U, Barker DJ (2022). Stress reveals a specific behavioral phenotype for opioid abuse susceptibility, Journal of the Experimental Analysis of Behavior. https://doi.org/10.1002/jeab.738

2021

Coffey KR, Venkat V, West MO, Barker DJ(2021). Lateral preoptic area neurons signal cocaine self-administration behaviors, European Journal of Neuroscience 2021 Sep 09 ;https://doi.org/10.1111/ejn.15452

Dieterich, A., Floeder, J., Stech, K., Lee, J., Srivastava, P, Barker, D.J., Samuels, B.A. (2021) Activation of Basolateral Amygdala to Nucleus Accumbens Projection Neurons Attenuates Chronic Corticosterone-Induced Behavioral Deficits in Male Mice. Frontiers in Behavioral Neuroscience.

Bruno, C.A., O’Brien, C., Bryant, S., Mejaes, J., Pizzano, C., Estrin, D.J., Barker, D.J. (2020) pMAT: An Open-Source Software Suite for the Analysis of Fiber Photometry Calcium Imaging. Pharmacology, Biochemistry and Behavior. Dec 29;201:173093. doi: 10.1016/j.pbb.2020.173093.

Pignatelli,M., Tejeda, H.A., Barker, D.J., Bontempi, L., Wu, J., Lopez, A., Palma Ribeiro, S., Lucantonio, F., Parise, E.M., Torres-Berrio, A., Alvarez-Bagnarol, Y., Marino, R., Cai, Z., Xue, M., Morales, M., Tamminga, C.A., Nestler, E.J., Bonci, A. (2021). Cooperative synaptic and intrinsic plasticity in a disynaptic limbic circuit drives stress-induced anhedonia and passive coping in mice. Molecular Psychiatry (in press). [Download]

2020

Root DH*, Barker DJ*, Estrin DJ, Miranda J, Liu B, Zhang S, Wang HL, Vautier F, Ramakrishnan C, Kim Y, Fenno L, Deisseroth K, Morales M. (2020). Distinct signaling by VTA glutamate, GABA, and combinatorial glutamate-GABA neurons in motivated behavior, Cell Reports. 2020 Sep 1;32(9):108094. doi: 10.1016/j.celrep.2020.108094 * Equal Contribution

Barbano, M.F., Wang, H.L, Zhang, S. Miranda-Barrientos, J., Estrin, D.J., Figueroa-Gonzalez, A., Liu, B., Barker, D.J., Morales, M. (2020). VTA Glutamatergic Neurons Mediate Innate Defensive Behaviors. Neuron (in press). [Download]

2018

Root, D. H., Zhang, S., Barker, D. J., Miranda-Barrientos, J., Liu, B., Wang, H. L., & Morales, M. (2018). Selective brain distribution and distinctive synaptic architecture of dual glutamatergic-GABAergic neurons. Cell reports, 23(12), 3465-3479.

Barker, DJ (2018). Ultrasonic Vocalizations as an Index of Positive Emotional State. Handbook of Behavioral Neuroscience, 25, 253-260.

Simmons, SJ, Barker, DJ, & West, MO (2018). Ultrasonic Vocalizations Capture Opposing Affective States During Drug Self-Administration: Revisiting the Opponent-Process Model of Addiction. Handbook of Behavioral Neuroscience, 25, 389-399.

Lo, M, Wang S, Singh S, Damodaran VB, Coffey K, Barker DJ, Saste K, Kals, K, Kaplan HM, Kohn J, Shreiber DI, Zahn JD. (2018) Evaluating the in vivo glial response to miniaturized parylene cortical probes coated with an ultra-fast degrading polymer to aid insertion. Journal of neural engineering, 15(3), 036002. [Download]

Simmons SJ, Gregg RA, Tran FH, Mo L, vonWeltin E, Barker DJ, Gentile TA, Watterson LR, Rawls SM, Muschamp JW. (2018) Comparison of the rewarding and reinforcing effects of ‘bath salt’ 3,4-methylenedioxypyrovalerone (MDPV) and cocaine using ultrasonic vocalizations in rats. Addiction Biology, doi: 10.1111/adb.12479. [Download]

Gentile TA, Simmons SJ, Barker DJ, Shaw JK, España RA, Muschamp JW (2018). Suvorexant, an orexin/hypocretin receptor antagonist, attenuates the motivational and hedonic properties of cocaine. Addiction biology, 23(1), 247-255. [Download]

2017

Barker DJ, Root DH, Zhang S, Miranda-Barrientos J, Wang HL, Morales M. (2017) Lateral preoptic control of the lateral habenula through convergent glutamate and GABA transmission. Cell reports, 21(7), 1757-1769. [Download]

Barker, DJ, & Johnson, AM (2017). Automated acoustic analysis of 50-kHz ultrasonic vocalizations using template matching and contour analysis. The Journal of the Acoustical Society of America, 141(3), EL281-EL286. [Download]

Campbell EJ, Barker DJ, Nasser HM, Kaganovsky K, Dayas CV, Marchant NJ. (2017)  Cue-induced food seeking after punishment is associated with increased Fos expression in the lateral hypothalamus, basolateral and medial amygdala. Behav. Neurosci, doi: 10.1037/bne0000185. [Download]

2016

Barker DJ, Root DH, Zhang S, Morales M. (2016). Multiplexed neurochemical signaling by neurons of the ventral tegmental area. pii: S0891-0618(16)00002-8. doi: 10.1016/j.jchemneu.2015.12.016. [Download]
*2016 Neuroscience highly-cited collection

Root DH, Wang HL, Liu B, Barker DJ, Silva AC, Magloczky Z, Morales M. (2016) Dopamine neurons in the midbrain of nonhuman primates and humans are intermingled with glutamatergic and dual glutamatergic-dopaminergic neurons. Scientific Reports, Article 30615, doi:10.1038/srep30615. [Download]

Qi J, Zhang S ,Wang HL, Barker DJ, Miranda-Barrientos J, Morales M. (2016) VTA glutamatergic inputs to nucleus accumbens drive aversion by acting on GABAergic interneurons. Nature Neuroscience, 19(5): 725-33, doi: 10.1038/nn.4281. [Download]

2015

Barker DJ, Simmons SJ, West MO (2015). Ultrasonic vocalizations as a measure of affect in preclinical models of drug abuse: A review of current findings. Current Neuropharmacology, 13(2):193-210. [Download]

Coffey K*, Barker DJ*, Gayliard N, Kulik J, Pawlak AP, West MO (2015). Electrophysiological evidence of alterations to the nucleus accumbens and dorsolateral striatum during chronic cocaine self-administration. Eur J. Neurosci, 41(12):1538-52. doi: 10.1111/ejn.12904. [Download] * Equal Contributions.

Barker DJ, Striano BM, Pawlak AP, Kim O, Root DH, Fabbricatore AT, West MO. (2015) Sensitivity to self-administered cocaine within the lateral preoptic-rostral lateral hypothalamic continuum. Brain Struct Funct, 220(3):1841-54. doi: 10.1007/s00429-014-0736-6. [Download]

Ma S, Barker DJ. (2015). Predicting spiking activities in DLS neurons with linear-nonlinear-poisson model. JMLR: Workshop and Conference Proceedings, 11:85-92. [Download]

2014

Barker DJ, Herrera C, West MO. (2014) Automated detection of 50-kHz ultrasonic vocalizations using template matching in XBAT. J. Neurosci Methods, 236:68-75 doi: 10.1016/j.jneumeth.2014.08.007. [Download]

Barker DJ, Bercovicz D, Servilio LC, Simmons SJ, Ma A, Root DH, Pawlak AP, West MO (2014). Rat Ultrasonic Vocalizations Demonstrate that the Motivation to Contextually Reinstate Drug-Seeking Behavior does not Necessarily Involve a Hedonic Response. Addiction biology, 19(5), 781-790 doi: 10.1111/adb.12044. [Download]

Striano, BM, Barker DJ, Pawlak AP, Root DH, Coffey KR, Fabbricatore AT, West MO.  (2014) Olfactory Tubercle neurons exhibit slow-phasic firing patterns during cocaine self-administration. Synapse, 68 (7): 321-3. [Download]

Barker DJ, Simmons SJ, Servilio LC,  Bercovicz D, Root DH, Ma S, West MO (2014). Ultrasonic vocalizations: evidence for an affective opponent process during cocaine self-administration. Psychopharmacology,231(5):909-918. [Download]

Barker DJ. (2014). Making WAAVES in the vocalization community, but how big is the splash? J. Neuroscience Methods, 221:-228-229. [Download]

Barker DJ, Coffey KR, Ma S, Root DH, West MO. (2014). A procedure for implanting  organized arrays of microwires for single-unit recordings in the awake behaving animal. J Vis Exp, (84):e51004. [Download]

2013

Coffey KR, Barker DJ, Ma S, West MO. (2013). Building an open-source robotic stereotaxic instrument. J Vis. Exp, (80), e51006, doi:10.3791/51006. [Download]

Ma S, Cho J, Root DH, Barker DJ, Pawlak AP, West MO. (2013) Amphetamine’s Dose-   dependent effects on dorsolateral striatum sensorimotor neuron firing. Behav. Brain Res, 244: 152-61. [Download]

Coffey KR, Barker DJ, Ma S, Root DH, Martinez L, Horvitz JC, West MO (2013) Effect of varying reinforcement probability on Pavlovian approach behavior and ultrasonic vocalizations in rats. Behav. Brain Res, 237: 256-262. [Download]

Root DH, Ma S, Barker DJ, Megehee L, Striano BM, Ralston CM, Fabbricatore AT, West MO (2013). Differential roles of ventral pallidum subregions during cocaine self-administration behaviors. J Comp. Neurol 521(3): 558-88. [Download]

2012

Root DH, Fabricatore AT, Pawlak AP, Barker DJ, Ma S, West MO (2012). Slow Phasic and tonic activity of ventral pallidal neurons during cocaine self-administration. Synapse, 66(2):106-127. [Download]

2011

Root DH, Barker DJ, Ma S, Coffey KR, Fabbricatore AT, West MO (2011). Evidence for learned skill during cocaine self-administration in rats. Psychopharmacology 217(1):91-100. [Download]

2010

Barker DJ, Root DH, Ma S, Jha S, Megehee L, Pawlak AP, West MO. (2010). Dose dependent differences in short ultrasonic vocalizations emitted by rats during cocaine self-administration. Psychopharmacology 211(4): 435-442. [Download]

Barker DJ, Sanabria F, Lasswell A, Thrailkill EA, Pawlak AP, Killeen PR. (2010). Brief light as a practical aversive stimulus for the albino rat. Behav. Brain Res 214(2): 402-408. [Download]

Root DH, Fabbricatore AT, Ma S, Barker DJ, West MO. (2010) Rapid phasic activity of ventral pallidal neurons during cocaine self-administration. Synapse 64(9): 704-713. [Download]

2009

Tang CC,  Root DH,  Duke DC, Zhu Y, Teixeria K, Ma S, Barker DJ, West MO. (2009). Decreasing firing of striatal neurons related to licking during acquisition and overtraining of a licking task. J. Neurosci 29(44): 13952-13961. [Download]

Root DH, Fabbricatore AT, Barker DJ, Ma S, Pawlak AP, West MO. (2009). Evidence for habitual and goal directed behavior following devaluation of cocaine: a multifaceted interpretation of relapse. PloS One 4: e7170. [Download]

Root DH, Barker DJ, Ma S. (2009). Duality of salience in dopamine neurons. PNAS 106(31): E84. [Download]